Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143158 | 0.88 | ALDH1A1 (0.47) | DRD1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2094236 | 0.80 | ALDH1A3 (0.57) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL29452896 | 0.79 | DRD1 (0.47) | DRD1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13374000 | 0.78 | ALDH1A1 (0.45) | DRD1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27582585 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL469386 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1LMNAALOX15 | |
| SCHEMBL11065049 | 0.75 | DRD1 (0.56) | DRD1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL22678857 | 0.73 | DRD1 (0.42) | DRD1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7295754 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL14353698 | 0.72 | ROCK1 (0.47) | DRD1ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| CN-115066417-B | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-115066417-A | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |
| WO-2021136390-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR | 上海京新生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021136390-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR | 上海京新生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |