Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140538 | 0.96 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL25812313 | 0.93 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL63717 | 0.93 | TSHR (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28347564 | 0.91 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Alcohol SCHEMBL28778173 | 0.90 | TSHR (0.51) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL221515 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Butanone SCHEMBL28158317 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL486167 | 0.88 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2237451 | 0.88 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1070990 | 0.88 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | disclosed |