Sugi Predict

Sugi Predict / Compounds / SCHEMBL140538

SCHEMBL140538

SCHEMBL140538

C=C(C)C(=O)OCCC[Si](C)(OCCCC)OCCCC

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.60
▸ THRB P10828 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.43
▸ POLB P06746 2/20 0.40
▸ APEX1 P27695 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ HPGD P15428 1/20 0.39
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ ACHE P22303 6/20 0.33
▸ HCAR2 Q8TDS4 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7710883 0.96 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1070990 0.92 TSHR (0.57) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2237451 0.92 TSHR (0.57) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL25812313 0.88 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL3503924 0.88 TSHR (0.60) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8899367 0.88 TSHR (0.60) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL63717 0.87 TSHR (0.54) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28347564 0.86 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL72364 0.86 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8900512 0.86 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 961 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 — — WO claimed
CN-112533910-B Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2024-05-10 — — CN claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 — — US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 — — US claimed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 — — CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 — — EP claimed
US-20170298026-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-10-19 — — US claimed
EP-3204353-A1 ALL PURPOSE RAFT AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2017-08-16 — — EP claimed
US-20160340463-A1 PROCESS FOR PREPARING A POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2016-11-24 — — US claimed
WO-2016054689-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-04-14 — — WO claimed
US-6037008-A APPLYING AN ADHESION PROMOTING ORGANOSILANE PRIMER COMPOSITION TO A SUBSTRATE SURFACE, APPLYING A CURABLE SEALANT, ADHESIVE OR COATING FORMULATION TO THE PRIMED SUBSTRATE, AND ALLOWING SAID SEALANT, ADHESIVE OR COATING TO CURE CK WITCO CORPORATION 2000-03-14 — — US claimed
WO-1999009077-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-25 — — WO claimed
WO-1999005099-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-04 — — WO claimed
EP-0665252-B1 Two-pack aqueous coating composition KANSAI PAINT CO LTD (JP) 1998-12-16 — — EP claimed
US-5847060-A Functionalized diene oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-08 — — US claimed
US-5686523-A OF A SATURATED ALKOXY SILANE, AN EMULSIFIER, WATER AND A WATER DISPERSIBLE OR EMULSIFIED POLYMER CONTAINING AN ALKOXY SILANE FUNCTIONAL GROUP OSI SPECIALTIES, INC. (US) 1997-11-11 — — US claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 — — EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 — — WO claimed
US-5519089-A ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE KANSAI PAINT CO., LTD. (JP) 1996-05-21 — — US claimed
EP-0665252-A2 Two-pack aqueous coating composition KANSAI PAINT CO., LTD. (JP) 1995-08-02 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885THRB 4861/4885ALDH1A1 581/4885
US-20170298026-A1 ALL PURPOSE RAFT AGENT NPC1L1, RFTN1, SGMS2 TSHR 4058/4885THRB 4068/4885ALDH1A1 817/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885THRB 4861/4885ALDH1A1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.