Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140538 | 0.92 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2246405 | 0.90 | TSHR (0.51) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7710883 | 0.88 | TSHR (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2239148 | 0.85 | TSHR (0.59) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5699018 | 0.85 | TSHR (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL65280 | 0.85 | THRB (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1070990 | 0.84 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL8899367 | 0.83 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11765241 | 0.83 | TSHR (0.56) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3503924 | 0.83 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994250-B2 | Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof | KONISHI CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090326151-A1 | HAIR COSMETIC | KONISHI CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2039347-A1 | COSMETIC HAIR PREPARATION | Shiseido Company, Limited (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-1837360-A1 | VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME | Konishi Co., Ltd. (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20070117902-A1 | Vinyl-urethane copolymers and production methods thereof | KONISHI CO., LTD. (JP) | 2007-05-24 | — | — | US | disclosed |
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |