SCHEMBL7710952

SCHEMBL7710952

CCc1c(CC)n(C)c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 5/20 0.58
TSHR P16473 4/20 0.58
HTT P42858 2/20 0.58
LMNA P02545 2/20 0.58
GPR3 P46089 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
SLC2A1 P11166 1/20 0.51
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
EGFR P00533 4/20 0.42
NPEPPS P55786 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.40
FTO Q9C0B1 1/20 0.40
NPC1 O15118 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19539157 0.89 KDM4E (0.60) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL10237505 0.84 ALDH1A1 (0.48) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL15107054 0.80 GPR3 (0.52) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL1925036 0.80 GPR3 (0.58) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL10235160 0.78 ALDH1A1 (0.66) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL13884612 0.78 GPR3 (0.50) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL7707734 0.77 KDM4E (0.40) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL10652634 0.76 ALDH1A1 (0.69) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL14079402 0.76 GPR3 (0.47) KDM4EALDH1A1TSHRHTTLMNA
SCHEMBL21939787 0.74 KDM4E (0.55) KDM4EALDH1A1TSHRHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523031-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-20 US disclosed
US-9523031-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-20 US disclosed
US-9371331-B2 Modulators of methyl modifying enzymes, compositions and uses thereof CONSTELLATION PHARMACEUTICALS, INC. (US) 2016-06-21 US disclosed
US-20150259351-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2015-09-17 US disclosed
US-7642272-B2 Cannabinoid receptor ligands SCHERING CORPORATION (US) 2010-01-05 US disclosed
US-20090091240-A1 COMPOUND CONTAINING FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-09 US disclosed
US-20090091240-A1 COMPOUND CONTAINING FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-09 US disclosed
US-20070224448-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-09-27 US disclosed
US-20070224448-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-09-27 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
EP-1808433-A1 COMPOUND CONTAINING FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 2007-07-18 EP disclosed
EP-1750487-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2007-02-07 EP disclosed
US-20070009760-A1 Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device INOUE TETSUYA 2007-01-11 US disclosed
US-20070009760-A1 Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device INOUE TETSUYA 2007-01-11 US disclosed
US-6386113-B1 ODORS FOR WEAPONS ECOLOGICAL TECHNOLOGIES CORPORATION 2002-05-14 US disclosed
US-6352032-B1 CONTAINMENT VESSEL MAY COMPRISE A ?PAINT BALL?; TOXICITY CATEGORY RATING OF AT LEAST III. ECOLOGICAL TECHNOLOGIES CORPORATION 2002-03-05 US disclosed
US-6242489-B1 ORGANIC SULFUR COMPOUND AND INTENSIFIER SUCH AS SKATOLE; NON-LETHAL WARFARE ECOLOGICAL TECHNOLOGIES CORPORATION 2001-06-05 US disclosed
EP-1086061-A2 MALODORANT COMPOSITIONS, RELATED NON-LETHAL WEAPON SYSTEMS, AND METHODS OF THEIR USE VRP Eco-Tek, Corp. (US) 2001-03-28 EP disclosed
WO-1999065847-A2 MALODORANT COMPOSITIONS, RELATED NON-LETHAL WEAPON SYSTEMS, AND METHODS OF THEIR USE VRP ECO-TEK, CORP. (US) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090091240-A1 COMPOUND CONTAINING FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME INTS9, KCNN2, KCNH3 KDM4E 1777/4885ALDH1A1 1559/4885TSHR 4522/4885
US-20150259351-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF TET1, TET3, EHMT2 KDM4E 76/4885ALDH1A1 1213/4885TSHR 4426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.