Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899987 | 0.81 | TSHR (0.39) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL20445740 | 0.81 | TSHR (0.39) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL28985628 | 0.81 | — | — | |
| SCHEMBL899985 | 0.81 | TSHR (0.39) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL689737 | 0.76 | — | — | |
| SCHEMBL28430514 | 0.75 | — | — | |
| SCHEMBL29681890 | 0.74 | SLC6A2 (0.46) | TSHRALDH1A1 | |
| SCHEMBL7710966 | 0.72 | ACMSD (0.38) | ALDH1A1 | |
| SCHEMBL6810189 | 0.70 | FGF23 (0.46) | TSHRALDH1A1 | |
| SCHEMBL94238 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986630-A | Optical waveguides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | claimed |
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |