Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29681890 | 0.98 | SLC6A2 (0.46) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL5006722 | 0.95 | FGF23 (0.50) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL6566571 | 0.85 | CFTR (0.42) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL8653245 | 0.82 | PTGS2 (0.54) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL8705170 | 0.79 | PTGS2 (0.52) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL30877921 | 0.79 | PTGS2 (0.52) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL30144760 | 0.79 | PTGS2 (0.52) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL8705175 | 0.79 | PTGS2 (0.52) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL8518215 | 0.76 | PTGS2 (0.59) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 | |
| SCHEMBL27874435 | 0.75 | KMT2A (0.46) | FGF23SLC6A2SLC6A4SLC6A3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57109743-A | — | — | None | — | — | JP | disclosed |
| US-20040116398-A1 | Therapeutic applications of estrogenic carboxylic acids | SOUTHERN ILLINOIS UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| US-6608111-B1 | Estrogenic carboxylic acids; administering bisdehydrodoisynolic acid | SOUTHERN ILLINOIS UNIVERSITY OFFICE OF RESEARCH, DEVELOPMENT AND ADMINISTRATION | 2003-08-19 | — | — | US | disclosed |
| WO-1999066915-A2 | THERAPEUTIC APPLICATIONS OF ESTROGENIC CARBOXYLIC ACIDS | SOUTHERN ILLINOIS UNIVERSITY AT CARBONDALE (US) | 1999-12-29 | — | — | WO | disclosed |
| JP-S57109743-A | PHENYLCYCLOHEXENE DERIVATIVE | SUNTORY LTD | 1982-07-08 | — | — | JP | disclosed |