Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713596 | 0.81 | NPC1 (0.51) | POLBMAPTRAB9ANPC1CHRNB2 | |
| SCHEMBL7775228 | 0.80 | NPC1 (0.57) | ELANEPOLBMAPTRAB9ANPC1 | |
| SCHEMBL8366016 | 0.80 | SMN1; SMN2 (0.46) | ELANEPOLBMAPTRAB9ANPC1 | |
| SCHEMBL17281256 | 0.80 | ELANE (0.56) | ELANEPOLBMAPTKMT2AMEN1 | |
| SCHEMBL5729777 | 0.79 | PARP10 (0.53) | POLBMAPTRAB9ANPC1CHRNB2 | |
| SCHEMBL17460993 | 0.79 | NPC1 (0.49) | POLBMAPTRAB9ANPC1CHRNB2 | |
| SCHEMBL9923605 | 0.79 | NPC1 (0.49) | POLBMAPTRAB9ANPC1CHRNB2 | |
| SCHEMBL25501082 | 0.78 | PTPN2 (0.43) | ELANEPOLBNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL9615830 | 0.77 | NPC1 (0.43) | ELANEPOLBMAPTRAB9ANPC1 | |
| SCHEMBL7711204 | 0.77 | NPC1 (0.47) | POLBMAPTRAB9ANPC1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300454-B1 | Liquid-crystalline nematic organosiloxanes which can be crosslinked to form optically anisotropic polymer layers | WACKER-CHEMIE GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0985721-B1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | CONSORTIUM ELEKTROCHEM IND (DE) | 2001-08-29 | — | — | EP | disclosed |
| EP-0985721-A1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | Consortium für elektrochemische Industrie GmbH (DE) | 2000-03-15 | — | — | EP | disclosed |