Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955951 | 0.86 | CKS1B (0.52) | DRD2ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL3436185 | 0.85 | CKS1B (0.54) | DRD2ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL7716756 | 0.84 | DRD2 (0.51) | DRD2DRD3 | |
| SCHEMBL14328884 | 0.83 | PIM1 (0.56) | DRD2ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL13495900 | 0.83 | PIM1 (0.56) | DRD2ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL14207420 | 0.82 | CKS1B (0.49) | DRD2ALDH1A1LMNAMAPTHSD11B1 | |
| SCHEMBL14206795 | 0.82 | CKS1B (0.48) | DRD2ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL7716782 | 0.82 | DRD2 (0.69) | DRD2DRD3 | |
| SCHEMBL14207434 | 0.81 | ALDH1A1 (0.51) | DRD2ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL7711219 | 0.81 | DRD2 (0.48) | DRD2ALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |