Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860751 | 0.90 | SLC2A1 (0.47) | SLC2A1ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6947506 | 0.78 | CA12 (0.47) | SLC2A1ALDH1A1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL852975 | 0.76 | POLB (0.40) | ALDH1A1HPGDHSD17B10KMT2APOLB | |
| SCHEMBL6951347 | 0.75 | CA12 (0.38) | ALDH1A1HSD17B10KMT2AKDM4EL3MBTL1 | |
| SCHEMBL3217738 | 0.75 | MAPT (0.42) | ALDH1A1HPGDHSD17B10KMT2APOLB | |
| SCHEMBL6177680 | 0.73 | KCNH3 (0.42) | ALDH1A1HPGDHSD17B10KMT2APOLB | |
| SCHEMBL17627325 | 0.73 | KDM4E (0.41) | SLC2A1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14182015 | 0.72 | NPSR1 (0.38) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL4638849 | 0.72 | LMNA (0.34) | ALDH1A1MAPTKDM4ETDP1LMNA | |
| SCHEMBL6963178 | 0.72 | KMT2A (0.34) | SLC2A1ALDH1A1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |