Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507884 | 0.89 | GPR35 (0.56) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL10879675 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| Nitric Acid SCHEMBL20985017 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KMT2ATSHRCYP3A4 | |
| SCHEMBL8446350 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GPR35KMT2ACYP19A1 | |
| SCHEMBL11291584 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL27501452 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL11879315 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| Allisan SCHEMBL229362 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR35KMT2ACYP19A1 | |
| SCHEMBL635165 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR35KMT2ACYP19A1 | |
| SCHEMBL10586234 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372774-B1 | THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2002-04-16 | — | — | US | disclosed |
| US-5916618-A | PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0234119-B1 | Pesticidal method using N-phenylpyrazoles | RHONE POULENC AGROCHIMIE (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0579280-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1994-01-19 | — | — | EP | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| US-4950678-A | PESTICIDES | SANDOZ LTD. (CH) | 1990-08-21 | — | — | US | disclosed |
| EP-0234119-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987003781-A1 | PESTICIDAL METHOD USING N-PHENYLPYRAZOLES | MAY & BAKER LIMITED (GB) | 1987-07-02 | — | — | WO | disclosed |
| US-4609620-A | CHROMOGENIC MONOCHROME NEGATIVES | CIBA GEIGY AG (CH) | 1986-09-02 | — | — | US | disclosed |
| EP-0089315-A2 | Pyrazolone compounds and a process for their manufacture | CIBA-GEIGY AG (CH) | 1983-09-21 | — | — | EP | disclosed |
| US-4113954-A | PROCESS FOR THE PREPARATION OF 3-ANILINO-5-PYRAZOLONES | GAF CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-3979412-A | Process for producing 3-anilino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JA) | 1976-09-07 | — | — | US | disclosed |
| US-3933874-A | Method for preparing of β-anilino-β-hydrazinoacrylates | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |