Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19745321 | 0.86 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL28960083 | 0.82 | KMT2A (0.35) | KMT2AMEN1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL8493070 | 0.79 | KMT2A (0.41) | KMT2AMEN1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL10591414 | 0.79 | KMT2A (0.40) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL4947041 | 0.74 | MEN1 (0.32) | KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL4947035 | 0.73 | MEN1 (0.39) | KMT2AMEN1MTNR1AMTNR1BLMNA | |
| SCHEMBL8392334 | 0.72 | NPSR1 (0.43) | KMT2AMEN1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL8394621 | 0.71 | FAAH (0.39) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL3977766 | 0.71 | ALDH1A1 (0.54) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6037494 | 0.71 | NPSR1 (0.41) | KMT2AMEN1MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365359-B1 | IDENTIFYING PRP PHARMACORE BY DETERMINING FUNCTIONAL RESIDUES OF PROTEIN INVOLVED IN COMPLEX INTERACTIONS, DEVELOPING THREE DIMENSIONAL STRUCTURES, COMPARING THEM WITH OTHER COMPOUNDS AND IDENTIFYING COMPOUNDS CONSISTENT WITH BINDING TO PROTEIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-02 | — | — | US | disclosed |