Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289841 | 0.81 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL5734959 | 0.77 | SIGMAR1 (0.37) | MEN1KMT2A | |
| SCHEMBL8493070 | 0.75 | KMT2A (0.41) | MEN1KMT2AMTNR1AMTNR1B | |
| Acetic Acid SCHEMBL28077703 | 0.75 | KMT2A (0.35) | MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7711518 | 0.74 | KMT2A (0.33) | MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL19745321 | 0.69 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL10591414 | 0.67 | KMT2A (0.40) | MEN1KMT2A | |
| SCHEMBL6037494 | 0.67 | NPSR1 (0.41) | MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL13499619 | 0.67 | L3MBTL1 (0.46) | MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL3977766 | 0.67 | ALDH1A1 (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218360-B1 | TRIAZINE KINASE INHIBITORS | AMGEN INC (US) | 2008-05-28 | — | — | EP | disclosed |
| US-7074789-B2 | Kinase inhibitors | AMGEN INC. (US) | 2006-07-11 | — | — | US | disclosed |
| US-20040116388-A1 | triazine compoound inhibitors of enzymes that catalyze phosphoryl transfer and/or that bind ATP/GTP nucleotides | AMGEN INC. | 2004-06-17 | — | — | US | disclosed |
| EP-1218360-A1 | TRIAZINE KINASE INHIBITORS | Amgen Inc., (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025220-A1 | TRIAZINE KINASE INHIBITORS | AMGEN INC. (US) | 2001-04-12 | — | — | WO | disclosed |