Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986529 | 0.87 | ELANE (0.36) | PTGS1ALDH1A1 | |
| SCHEMBL8673237 | 0.77 | ACHE (0.44) | PTGS1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL9426682 | 0.77 | MAPK1 (0.45) | PTGS1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL9148761 | 0.76 | CFD (0.41) | PTGS1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL24817230 | 0.76 | TUBB1 (0.38) | PTGS1KDM4EALDH1A1GAA | |
| SCHEMBL156400 | 0.76 | CYP4F2 (0.51) | PTGS1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL31621880 | 0.76 | CYP4F2 (0.51) | PTGS1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL1088271 | 0.75 | HTT (0.47) | PTGS1TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL27687896 | 0.75 | PTGS1 (0.47) | PTGS1TSHRALDH1A1GAARAB9A | |
| SCHEMBL28078759 | 0.75 | MAPK1 (0.42) | PTGS1TSHRKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369279-B1 | STYRENE WITH ETHER OR FLUORINE GROUPS FOR POLYMERS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-04-09 | — | — | US | disclosed |