Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CDC42 | P60953 | 1/20 | 0.71 |
| ▸ | RAC1 | P63000 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18818204 | 0.94 | PTGS2 (0.68) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29597190 | 0.90 | PTGS2 (0.66) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL30881594 | 0.90 | PTGS2 (0.66) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL2884705 | 0.90 | PTGS2 (0.66) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL14962625 | 0.89 | TDP1 (0.61) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL9551659 | 0.89 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29403959 | 0.89 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505811 | 0.89 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505819 | 0.89 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29508603 | 0.89 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369260-B1 | ANTIAGGLOMERANTS AND ANTICOAGULANTS | LABORATORI ALCHEMICA S.R.L. (IT) | 2002-04-09 | — | — | US | disclosed |