Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CDC42 | P60953 | 1/20 | 0.59 |
| ▸ | RAC1 | P63000 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881594 | 1.00 | PTGS2 (0.66) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL29597190 | 1.00 | PTGS2 (0.66) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL7712563 | 0.90 | TDP1 (0.75) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| Atb-346 SCHEMBL23643163 | 0.90 | PTGS2 (0.63) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| Atb-346 SCHEMBL31566275 | 0.90 | PTGS2 (0.63) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| Atb-346 SCHEMBL29358559 | 0.90 | PTGS2 (0.63) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| Atb-346 SCHEMBL29596141 | 0.90 | PTGS2 (0.63) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| Atb-346 SCHEMBL2883303 | 0.90 | PTGS2 (0.63) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL14962625 | 0.86 | TDP1 (0.61) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL18818204 | 0.85 | PTGS2 (0.68) | PTGS2TDP1L3MBTL1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076616-A1 | POLYMORPHIC FORMS OF OTENAPROXESUL AND COMPOSITIONS AND USES THEREOF | ANTIBE THERAPEUTICS INC. (CA) | 2025-04-17 | — | — | WO | disclosed |
| WO-2022115952-A1 | [1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-ACETIC ACID 4-THIOCARBAMOYL-PHENYL ESTER FOR THE TREATMENT OF A VIRAL INFECTION | ANTIBE THERAPEUTICS INC. (CA) | 2022-06-09 | — | — | WO | disclosed |
| CN-101501018-B | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC | 2014-08-27 | — | — | CN | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| EP-2057139-B1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| US-20090306412-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2009-12-10 | — | — | US | disclosed |
| CN-101501018-A | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC (CA) | 2009-08-05 | — | — | CN | disclosed |
| CN-101490029-A | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC (CA) | 2009-07-22 | — | — | CN | disclosed |
| EP-2057139-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | Antibe Therapeutics Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-2041108-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | Antibe Therapeutics Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008009118-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008009127-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306412-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | HRH4, HRH2, HNMT | PTGS2 125/4885TDP1 2411/4885L3MBTL1 2932/4885 |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | PTGS1, HPGDS, PTGES | PTGS2 4/4885TDP1 4498/4885L3MBTL1 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.