Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710152 | 0.87 | MAPT (0.43) | KMT2AMEN1ESR1POLBESR2 | |
| SCHEMBL7712652 | 0.80 | MAPT (0.46) | KMT2AMEN1POLBRAB9AL3MBTL1 | |
| SCHEMBL7713950 | 0.77 | ESR1 (0.43) | KMT2AMEN1ESR1ESR2NPC1 | |
| SCHEMBL7712642 | 0.76 | L3MBTL1 (0.40) | KMT2AMEN1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7707836 | 0.75 | KDM4E (0.48) | KMT2ARAB9AL3MBTL1MAPTHTT | |
| SCHEMBL29371006 | 0.73 | NPC1 (0.47) | KMT2AMEN1ESR1ESR2NPC1 | |
| SCHEMBL29368995 | 0.73 | KMT2A (0.48) | KMT2AMEN1ESR1POLBESR2 | |
| SCHEMBL29371981 | 0.72 | KMT2A (0.45) | KMT2AMEN1ESR1POLBESR2 | |
| SCHEMBL7714721 | 0.71 | CYP1A2 (0.37) | SMN1; SMN2L3MBTL1MAPTHTTCYP1A2 | |
| SCHEMBL31210171 | 0.71 | KMT2A (0.59) | KMT2AMEN1ESR1POLBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | disclosed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | C3AR1, C5AR2, TLR2 | KMT2A 804/4885MEN1 2948/4885ESR1 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.