Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710152 | 0.82 | MAPT (0.43) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL29368592 | 0.81 | KDM4E (0.47) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL7712641 | 0.80 | KMT2A (0.47) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL8837593 | 0.78 | GAA (0.57) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL9430129 | 0.74 | HTT (0.57) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL3006462 | 0.73 | KDM4E (0.48) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL9642267 | 0.73 | ABCB11 (0.55) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL7714721 | 0.72 | CYP1A2 (0.37) | MAPTTDP1L3MBTL1HTTCYP1A2 | |
| SCHEMBL8781224 | 0.72 | MAPT (0.43) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL27615297 | 0.72 | KDM4E (0.51) | MAPTKDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | disclosed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | disclosed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | disclosed |
| US-3941836-A | SOLUBILIZERS, PLASTICIZER, UV ABSORBER | THE LUBRIZOL CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | C3AR1, C5AR2, TLR2 | MAPT 4591/4885KDM4E 1082/4885ALDH1A1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.