Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.45 |
| ▸ | HMBS | P08397 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337759 | 0.75 | HMBS (0.50) | HMBSSPRKDM4EUSP2HPGD | |
| SCHEMBL15059806 | 0.75 | GAA (0.51) | GSK3BPTPN1HPGDSKDM4EALDH1A1 | |
| SCHEMBL7712966 | 0.72 | STING1 (0.40) | HMBSKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL17624955 | 0.68 | ALOX15 (0.42) | GSK3BHMBSHPGDKMT2A | |
| SCHEMBL18900582 | 0.68 | HMBS (0.42) | HMBSSPRKDM4EUSP2HPGD | |
| SCHEMBL23156354 | 0.64 | GSK3B (0.38) | GSK3BPTPN1HPGDSMAPT | |
| SCHEMBL6345873 | 0.64 | — | — | |
| SCHEMBL5591290 | 0.62 | — | — | |
| SCHEMBL227355 | 0.62 | GSK3B (1.00) | GSK3BPTPN1MEN1ALDH1A1MAPT | |
| SCHEMBL9788990 | 0.62 | PTPN1 (0.51) | GSK3BPTPN1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |