Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | HMBS | P08397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706783 | 1.00 | STING1 (0.40) | STING1MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL24630421 | 0.74 | HMBS (0.42) | MAPTL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL7712979 | 0.72 | GSK3B (0.45) | MAPTALDH1A1HPGDHMBSKDM4E | |
| SCHEMBL25139462 | 0.71 | HMBS (0.36) | MAPTL3MBTL1LMNAHMBSKDM4E | |
| SCHEMBL8775647 | 0.69 | ALDH1A1 (0.58) | MAPTL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL135355 | 0.68 | L3MBTL1 (0.66) | MAPTL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL9337759 | 0.68 | HMBS (0.50) | ALDH1A1LMNAHPGDSMN1; SMN2HMBS | |
| SCHEMBL11161484 | 0.64 | KMT2A (0.57) | MAPTL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL4686815 | 0.64 | MEN1 (0.54) | MAPTL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL8306301 | 0.64 | POLB (0.64) | MAPTL3MBTL1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |