Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119190 | 0.86 | ESR1 (0.49) | ESR1ESR2MAPTHSD17B10TP53 | |
| SCHEMBL1834878 | 0.82 | HSPA5 (0.64) | ESR1ESR2MAPTHSD17B10TP53 | |
| SCHEMBL7705080 | 0.81 | ALDH1A1 (0.43) | ESR1ESR2MAPTHSD17B10TP53 | |
| SCHEMBL21250284 | 0.81 | ESR1 (0.56) | ESR1ESR2MAPTHSD17B10GAA | |
| SCHEMBL15248109 | 0.80 | AMY1A (0.67) | ESR1ESR2MAPTHSD17B10TRPA1 | |
| SCHEMBL18287640 | 0.80 | ESR1 (0.59) | ESR1ESR2MAPTHSD17B10TP53 | |
| SCHEMBL14708688 | 0.80 | HSPA5 (0.67) | ESR1ESR2MAPTHSD17B10KEAP1 | |
| SCHEMBL10049007 | 0.80 | HSPA5 (0.67) | ESR1ESR2MAPTHSD17B10KEAP1 | |
| SCHEMBL28298946 | 0.79 | ESR1 (0.63) | ESR1ESR2MAPTHSD17B10TP53 | |
| SCHEMBL3306785 | 0.79 | ESR1 (0.47) | ESR1ESR2MAPTHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344524-B2 | Brain derived PPARα ligands | RUSH UNIVERSITY MEDICAL CENTER (US) | 2022-05-31 | — | — | US | disclosed |
| US-20200206177-A1 | Brain Derived PPARa Ligands | RUSH UNIVERSITY MEDICAL CENTER (US) | 2020-07-02 | — | — | US | disclosed |
| US-6365634-B1 | CUMYLPHENOL; NONSTEROIDAL ANTIINFLAMMATORY AGENT; FROM PEAT BOG | C-P TECHNOLOGY LIMITED PARTNERSHIP | 2002-04-02 | — | — | US | disclosed |
| US-4071565-A | SUBSTITUTED PHENOLS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-3989665-A | Butylated, α-methyl styrenated phenolic antioxidants for polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-11-02 | — | — | US | disclosed |