SCHEMBL7713575

SCHEMBL7713575

COc1ccc(C)cc1N1CCN(CC(O)COc2ccc(O)cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
MAPT P10636 5/20 0.61
TP53 P04637 2/20 0.61
USP2 O75604 1/20 0.60
TSHR P16473 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
KCNH2 Q12809 2/20 0.58
CACNA1G O43497 1/20 0.58
ABCB1 P08183 1/20 0.56
LMNA P02545 1/20 0.56
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7711550 0.99 MEN1 (0.66) MEN1KMT2AMAPTTP53USP2
SCHEMBL7708510 0.91 MEN1 (0.61) MEN1KMT2AMAPTKCNH2CACNA1G
Hydrochloric Acid SCHEMBL7711584 0.90 MEN1 (0.63) MEN1KMT2AMAPTSMN1; SMN2KCNH2
SCHEMBL7711663 0.89 KMT2A (0.64) MEN1KMT2AMAPTTP53USP2
SCHEMBL7705078 0.85 MEN1 (0.61) MEN1KMT2AMAPTKCNH2CACNA1G
Hydrochloric Acid SCHEMBL7711666 0.84 MEN1 (0.63) MEN1KMT2AMAPTTP53SMN1; SMN2
SCHEMBL7713556 0.83 MEN1 (0.64) MEN1KMT2AMAPTTP53USP2
Hydrochloric Acid SCHEMBL7713489 0.82 MEN1 (0.66) MEN1KMT2AMAPTTP53SMN1; SMN2
SCHEMBL2021538 0.81 MAPT (0.80) MEN1KMT2AMAPTTP53USP2
SCHEMBL2021540 0.81 MAPT (0.80) MEN1KMT2AMAPTTP53USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358515-B2 ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA SENJU PHARMACEUTICAL CO., LTD. (JP) 2002-03-19 US claimed
US-20010008893-A1 HYDROQUINONE DERIVATIVES SENJU PHARMACEUTICAL CO., LTD. (JP) 2001-07-19 US claimed
EP-0972766-A1 HYDROQUINONE DERIVATIVES Senju Pharmaceutical Co., Ltd. (JP) 2000-01-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010008893-A1 HYDROQUINONE DERIVATIVES REN, AGTR1, AGTR2 MEN1 2775/4885KMT2A 2128/4885MAPT 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.