Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099687 | 0.91 | NAAA (0.61) | FAAHNAAAMEN1KMT2AACHE | |
| SCHEMBL11619047 | 0.91 | NAAA (0.61) | FAAHNAAAMEN1KMT2AACHE | |
| SCHEMBL11232047 | 0.91 | NAAA (0.61) | FAAHNAAAMEN1KMT2AACHE | |
| SCHEMBL27331406 | 0.89 | PRMT1 (0.52) | NAAATSHRMAPK1EPHX2 | |
| SCHEMBL13356683 | 0.89 | ACHE (0.57) | ALDH1A1SMN1; SMN2FAAHNAAAACHE | |
| SCHEMBL27661517 | 0.89 | PRMT1 (0.52) | NAAATSHRMAPK1EPHX2 | |
| SCHEMBL7775670 | 0.86 | PAOX (0.37) | ALDH1A1SMN1; SMN2FAAHNAAAMEN1 | |
| SCHEMBL2943540 | 0.84 | TSHR (0.44) | ALDH1A1SMN1; SMN2FAAHNAAAMEN1 | |
| SCHEMBL22083675 | 0.83 | DNM1 (0.50) | ALDH1A1ACHETSHRKDM4E | |
| SCHEMBL10994200 | 0.83 | EPHX2 (0.60) | ALDH1A1MEN1KMT2ATDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | disclosed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | disclosed |