Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718638 | 0.89 | PRMT5 (0.36) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL7718645 | 0.88 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL7713764 | 0.74 | MAPT (0.77) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL21809365 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL12541627 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTHTTATM | |
| Hydrochloric Acid SCHEMBL29595529 | 0.70 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL12635066 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL11604652 | 0.65 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL9198947 | 0.65 | MAPT (0.75) | ALDH1A1LMNAMAPTHTTATM | |
| SCHEMBL6278621 | 0.64 | SMN1; SMN2 (0.58) | ALDH1A1LMNAHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |