Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | ATM | Q13315 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198947 | 0.90 | MAPT (0.75) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL7718161 | 0.87 | ALDH1A1 (0.60) | MAPTALDH1A1LMNAATMHTT | |
| Hydrochloric Acid SCHEMBL29595529 | 0.87 | ALDH1A1 (0.62) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL6862148 | 0.85 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL6202028 | 0.84 | ALDH1A1 (0.75) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL7713799 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL7720921 | 0.83 | POLB (0.54) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL7719197 | 0.82 | ALDH1A1 (0.71) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL10584214 | 0.79 | ALDH1A1 (0.97) | MAPTALDH1A1LMNAATMHTT | |
| SCHEMBL6320116 | 0.78 | SMN1; SMN2 (0.81) | MAPTALDH1A1LMNAATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |