Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.41 |
| ▸ | GABRP | O00591 | 5/20 | 0.41 |
| ▸ | GABRD | O14764 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.41 |
| ▸ | GABRE | P78334 | 5/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778899 | 1.00 | CA1 (0.46) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL30439201 | 0.84 | ALDH1A1 (0.50) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL964964 | 0.84 | GAA (0.50) | CA1CA2CA9GABRB3ALDH1A1 | |
| SCHEMBL967220 | 0.84 | ALDH1A1 (0.50) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL289233 | 0.84 | CA1 (0.43) | CA1CA2CA9GABRA2GABRB2 | |
| Hydrochloric Acid SCHEMBL29123267 | 0.82 | ALDH1A1 (0.48) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL17174592 | 0.81 | CA1 (0.41) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL18355927 | 0.81 | CA1 (0.41) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL3697730 | 0.81 | CA1 (0.41) | CA1CA2CA9ALDH1A1KDM4E | |
| Nitrogen SCHEMBL28714282 | 0.80 | ALDH1A1 (0.46) | CA1CA2CA9GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650345-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | BEIGENE SWITZERLAND GMBH (CH) | 2025-05-15 | — | — | US | disclosed |
| EP-4448513-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401514-A | 3, 4-Dihydroisoquinolin-1 (2H) -one derivatives as STING antagonists and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2024149242-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |
| CN-112313231-B | OGA inhibitor compounds | 詹森药业有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3810608-B1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2022-08-10 | — | — | EP | disclosed |
| US-11401271-B2 | Fused heterocyclic compound, pyrazole-ring-containing fused heterocyclic compound, agricultural composition containing thereof, and method of using the composition | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2022-08-02 | — | — | US | disclosed |
| US-20210188853-A1 | FUSED HETEROCYCLIC COMPOUND, PYRAZOLE-RING-CONTAINING FUSED HETEROCYCLIC COMPOUND, AGRICULTURAL COMPOSITION CONTAINING THEREOF, AND METHOD OF USING THE COMPOSITION | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2021-06-24 | — | — | US | disclosed |
| US-5916618-A | PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| EP-0295117-A1 | Derivatives of N-phenylpyrazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
| US-4237048-A | COLORFASTNESS; FOR DYEING NATURAL AND SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4105655-A | PHENYL-AZO-ANILINO DYESTUFF | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401271-B2 | Fused heterocyclic compound, pyrazole-ring-containing fused heterocyclic compound, agricultural composition containing thereof, and method of using the composition | SYMPK, DDT, CYP51A1 | CA1 1195/4885CA2 1393/4885CA9 1122/4885 |
| US-20210188853-A1 | FUSED HETEROCYCLIC COMPOUND, PYRAZOLE-RING-CONTAINING FUSED HETEROCYCLIC COMPOUND, AGRICULTURAL COMPOSITION CONTAINING THEREOF, AND METHOD OF USING THE COMPOSITION | SYMPK, DDT, CYP51A1 | CA1 1195/4885CA2 1393/4885CA9 1122/4885 |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | STING1, IRF3, MAVS | CA1 4877/4885CA2 4350/4885CA9 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.