Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886504 | 0.85 | TSHR (0.43) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7881875 | 0.81 | TSHR (0.50) | TSHRALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL7715831 | 0.81 | HCRTR1 (0.51) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL6887636 | 0.81 | TSHR (0.44) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL536025 | 0.80 | TSHR (0.71) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7870279 | 0.80 | ADRB2 (0.45) | TSHRALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL6886499 | 0.78 | HCRTR1 (0.43) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| Bicarbonate SCHEMBL5184189 | 0.77 | TSHR (0.67) | HCRTR1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7870110 | 0.76 | NPSR1 (0.56) | ALDH1A1SMN1; SMN2GAANPSR1MEN1 | |
| SCHEMBL8448318 | 0.76 | LMNA (0.54) | TSHRALDH1A1SMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |