Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719163 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7720938 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL23394687 | 0.83 | CHRM5 (0.36) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL21036085 | 0.83 | SIGMAR1 (0.37) | SMN1; SMN2CHRM5CHRM3ALDH1A1CA2 | |
| SCHEMBL13409018 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL4859643 | 0.80 | PPID (0.45) | KDM4EALDH1A1KMT2A | |
| SCHEMBL14066122 | 0.80 | PPID (0.45) | KDM4EALDH1A1KMT2A | |
| SCHEMBL7719250 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7718021 | 0.76 | CA2 (0.38) | CHRM5CHRM3CA2CA12CA1 | |
| SCHEMBL5967599 | 0.74 | KDM4E (0.51) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |