Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868501 | 0.86 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KMT2AITGB3ITGA2B | |
| SCHEMBL21035835 | 0.85 | CHEK1 (0.39) | SIGMAR1CHRM5CHRM3HPGDF2 | |
| SCHEMBL20994235 | 0.85 | CYP3A4 (0.40) | ALDH1A1SMN1; SMN2UGCGITGB3ITGA2B | |
| SCHEMBL20994238 | 0.85 | CYP3A4 (0.40) | ALDH1A1SMN1; SMN2UGCGITGB3ITGA2B | |
| SCHEMBL16748082 | 0.84 | SIGMAR1 (0.39) | SIGMAR1CHRM5CHRM3HPGDF2 | |
| SCHEMBL7713758 | 0.83 | SMN1; SMN2 (0.50) | CHRM5CHRM3ALDH1A1SMN1; SMN2F2 | |
| SCHEMBL17011282 | 0.82 | SIGMAR1 (0.37) | SIGMAR1CHRM5CHRM3HPGDF2 | |
| SCHEMBL23394687 | 0.79 | CHRM5 (0.36) | CHRM5CHRM3ALDH1A1SMN1; SMN2F2 | |
| SCHEMBL21124325 | 0.78 | PLD1 (0.36) | SIGMAR1F2 | |
| SCHEMBL21036475 | 0.78 | PLD1 (0.36) | SIGMAR1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489231-B1 | PIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3489231-A1 | PIPERAZINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |