Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713777 | 0.82 | HPGD (0.44) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL20561446 | 0.81 | KMT2A (0.55) | MAPTALDH1A1HTR1AHTR7MEN1 | |
| SCHEMBL7719186 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1HRH3MAPK1SMN1; SMN2 | |
| SCHEMBL7713799 | 0.77 | ALDH1A1 (0.56) | MAPTALDH1A1HTTHTR1AHTR7 | |
| SCHEMBL6862148 | 0.75 | ALDH1A1 (0.58) | MAPTALDH1A1HRH3MAPK1HTT | |
| SCHEMBL7718161 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1HRH3MAPK1HTT | |
| SCHEMBL11193055 | 0.71 | AKR1C3 (0.73) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL12541321 | 0.70 | MAPT (0.47) | MAPTALDH1A1HRH3MAPK1HTT | |
| SCHEMBL7718210 | 0.70 | KMT2A (0.50) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL6862144 | 0.70 | POLB (0.47) | MAPTALDH1A1MAPK1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |