Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862148 | 0.79 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9198270 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1GAAALDH1A1RAB9A | |
| SCHEMBL7718161 | 0.77 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7713723 | 0.76 | SLC6A4 (0.43) | ALDH1A1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7718668 | 0.76 | OPRK1 (0.45) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7719212 | 0.76 | SLC6A4 (0.48) | ALDH1A1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7713750 | 0.74 | ALDH1A1 (0.44) | KMT2AGAAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7718197 | 0.74 | RAB9A (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL6862360 | 0.73 | SLC6A4 (0.69) | KMT2AALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7719730 | 0.73 | GSK3B (0.43) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |