Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862148 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7713764 | 0.87 | MAPT (0.77) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7720921 | 0.87 | POLB (0.54) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL6862360 | 0.85 | SLC6A4 (0.69) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7719212 | 0.85 | SLC6A4 (0.48) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7713799 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7719244 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL14068950 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL6864372 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HTTRAB9AATMMITF | |
| SCHEMBL7718155 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTTRAB9AATMMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |