SCHEMBL7713784

SCHEMBL7713784

COc1cc(OC)nc(Oc2[c]cccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
NPSR1 Q6W5P4 2/20 0.40
CYP1A2 P05177 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP2C19 P33261 3/20 0.39
CYP3A4 P08684 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.39
ATM Q13315 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8322335 0.94 L3MBTL1 (0.45) L3MBTL1NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL7715933 0.75 L3MBTL1 (0.49) L3MBTL1NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL28313311 0.73
SCHEMBL9767808 0.73 L3MBTL1 (0.75) L3MBTL1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL2095414 0.72 ALDH1A1 (0.42) CYP1A2CYP2C9CYP2C19CYP3A4SMN1; SMN2
SCHEMBL1413 0.71
SCHEMBL10395477 0.71 ALDH1A1 (0.42) L3MBTL1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL7100899 0.71
SCHEMBL152163 0.71 LTA4H (0.32)
SCHEMBL1493266 0.71 MEN1 (0.39) CYP1A2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed