SCHEMBL771386

SCHEMBL771386

NC(=NO)c1ccc(O)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.76
LMNA P02545 5/20 0.50
RAB9A P51151 3/20 0.47
GAA P10253 2/20 0.47
RECQL P46063 2/20 0.47
KMT2A Q03164 2/20 0.44
GFER P55789 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 4/20 0.43
HSD17B10 Q99714 3/20 0.43
NPC1 O15118 2/20 0.43
ALOX15 P16050 2/20 0.43
TP53 P04637 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1187298 1.00 KDM1A (0.76) KDM1ALMNARAB9AGAARECQL
SCHEMBL12873713 1.00 KDM1A (0.76) KDM1ALMNARAB9AGAARECQL
SCHEMBL21215222 0.89 KDM1A (0.60) KDM1ALMNARAB9AGAARECQL
SCHEMBL10092621 0.81 KDM1A (0.54) KDM1ALMNARAB9AGAARECQL
SCHEMBL20017320 0.81 KDM1A (0.54) KDM1ALMNARAB9AGAARECQL
SCHEMBL8271836 0.79 KDM1A (0.52) KDM1ALMNARAB9AGAARECQL
SCHEMBL1269960 0.79 KDM1A (0.52) KDM1ALMNARAB9AGAARECQL
SCHEMBL15682614 0.79 KDM1A (0.52) KDM1ALMNARAB9AGAARECQL
SCHEMBL19411892 0.78 F12 (0.60) KDM1ALMNARAB9AGAARECQL
SCHEMBL17666232 0.78 F12 (0.60) KDM1ALMNARAB9AGAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 US disclosed
US-20240166638-A1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2024-05-23 US disclosed
EP-4361150-A2 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC Corporation (US) 2024-05-01 EP disclosed
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION 2024-03-21 US disclosed
EP-4262396-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2023-10-25 EP disclosed
WO-2023141114-A2 SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES LONG ISLAND UNIVERSITY (US) 2023-07-27 WO disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 US disclosed
WO-2022133114-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2022-06-23 WO disclosed
EP-3275440-B1 NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME NAT CT GERIATRICS & GERONTOLOGY (JP) 2022-05-04 EP disclosed
EP-3957636-A1 FUNGICIDAL OXADIAZOLES FMC Corporation (US) 2022-02-23 EP disclosed
EP-0566199-B1 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents SANOFI SA (FR) 2000-03-01 EP disclosed
EP-0625138-B1 NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS WITH LTB4 ANTAGONISTIC EFFECT BOEHRINGER INGELHEIM INT (DE) 1999-06-02 EP disclosed
EP-0902013-A1 Novel amidine derivatives, their preparation and their use as medicaments with LTB-4 antagonistic effect BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1999-03-17 EP disclosed
US-5643929-A TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES SANOFI WINTHROP, INC. (US) 1997-07-01 US disclosed
EP-0625138-A1 NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1994-11-23 EP disclosed
US-5349068-A 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1994-09-20 US disclosed
EP-0600586-A1 Photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-08 EP disclosed
WO-1993016036-A1 NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT BOEHRINGER INGELHEIM KG (DE) 1993-08-19 WO disclosed
US-5196535-A Viricides JANSSEN PHARMACEUTICA N.V. (BE) 1993-03-23 US disclosed
US-5100893-A Viricides, effective against picorna virus, durability JANSSEN PHARMACEUTICA N.V. (BE) 1992-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166638-A1 FUNGICIDAL OXADIAZOLES OXA1L, NOX1, TH KDM1A 1072/4885LMNA 3846/4885RAB9A 2129/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 KDM1A 1630/4885LMNA 2050/4885RAB9A 3078/4885
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES NOX1, TH, NOX3 KDM1A 1338/4885LMNA 3285/4885RAB9A 1660/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH KDM1A 1072/4885LMNA 3846/4885RAB9A 2129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.