Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592530 | 0.90 | HSD17B1 (0.42) | HSD17B1MAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL7717846 | 0.90 | HSD17B1 (0.46) | HSD17B1MAOBFFAR4TUBB4ATUBB | |
| SCHEMBL7712445 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL2591651 | 0.79 | HSD17B1 (0.44) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2593092 | 0.78 | HSD17B1 (0.43) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2591222 | 0.78 | HSD17B1 (0.46) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2593669 | 0.77 | HSD17B1 (0.42) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2591082 | 0.76 | HSD17B1 (0.44) | HSD17B1MAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2588295 | 0.76 | HSD17B1 (0.43) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2593665 | 0.76 | HSD17B1 (0.41) | HSD17B1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |