Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592229 | 0.90 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL7717394 | 0.90 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL7715665 | 0.87 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL7713141 | 0.85 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL7714650 | 0.83 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL7713890 | 0.81 | HSD17B1 (0.45) | — | |
| SCHEMBL2591573 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL2588129 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL14737779 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EHPGDS1PR1 | |
| SCHEMBL2591327 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHPGDS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |