Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76895 | 0.90 | LMNA (0.50) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL76522 | 0.90 | LMNA (0.50) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL13052942 | 0.89 | TDP1 (0.55) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL6707539 | 0.89 | ALDH1A1 (0.48) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL28457962 | 0.85 | TDP1 (0.55) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL14595547 | 0.83 | LMNA (0.56) | TDP1L3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL3376625 | 0.82 | SRC (0.52) | LMNAALDH1A1MTNR1AMTNR1BHPGD | |
| SCHEMBL4250144 | 0.82 | SRC (0.52) | LMNAALDH1A1MTNR1AMTNR1BHPGD | |
| SCHEMBL890060 | 0.82 | TACR3 (0.48) | ALDH1A1MTNR1AMTNR1BSRCCYP1A2 | |
| SCHEMBL627377 | 0.82 | SRC (0.52) | LMNAALDH1A1MTNR1AMTNR1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096138-B | Method for synthesizing alpha-aminoketone derivative | 郑州轻工业学院 | 2020-12-18 | — | — | CN | disclosed |
| CN-109096138-A | A method of synthesis α-amido ketone derivatives | 郑州轻工业学院 | 2018-12-28 | — | — | CN | disclosed |
| US-8129355-B2 | Nuclear receptor-based inducible gene expression system; modulating the expression of a gene in a host cell by introducing into the host cell a gene expression modulation system and activating that system using 5-ethyl-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid (1-benzoyl-cyclopentyl)-amide | INTREXON CORPORATION (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129355-B2 | Nuclear receptor-based inducible gene expression system; modulating the expression of a gene in a host cell by introducing into the host cell a gene expression modulation system and activating that system using 5-ethyl-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid (1-benzoyl-cyclopentyl)-amide | INTREXON CORPORATION (US) | 2012-03-06 | — | — | US | disclosed |
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |
| US-4194050-A | HYDROGENATING OXIMES HAVING AN ALPHA-HYDROGEN USING A RUTHENIUM CATALYST AND A CARBOXYLIC ANHYDRIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4137417-A | Process for producing an enamide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-01-30 | — | — | US | disclosed |