Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP10 | P09238 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714189 | 1.00 | KMT2A (0.46) | KMT2AKDM4ELMNAMEN1ALOX15 | |
| SCHEMBL6818563 | 0.87 | KMT2A (0.56) | KMT2ANPY1RL3MBTL1APP | |
| SCHEMBL7927436 | 0.87 | KMT2A (0.56) | KMT2ANPY1RL3MBTL1APP | |
| SCHEMBL7936884 | 0.87 | KMT2A (0.56) | KMT2ANPY1RL3MBTL1APP | |
| SCHEMBL7718985 | 0.86 | NPY1R (0.45) | KMT2ANPY1RL3MBTL1F10 | |
| SCHEMBL7718989 | 0.86 | NPY1R (0.45) | KMT2ANPY1RL3MBTL1F10 | |
| SCHEMBL7714010 | 0.85 | SLC16A3 (0.40) | KMT2ANPY1RL3MBTL1 | |
| SCHEMBL1065805 | 0.82 | SCN9A (0.50) | KMT2AKDM4EMEN1NPY1RPOLB | |
| SCHEMBL1065804 | 0.82 | SCN9A (0.50) | KMT2AKDM4EMEN1NPY1RPOLB | |
| SCHEMBL2332156 | 0.81 | FNTA (0.46) | KMT2ANPY1RFAAHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |