Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 6/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 6/20 | 0.40 |
| ▸ | MCTS1 | Q9ULC4 | 6/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714192 | 0.85 | KMT2A (0.46) | L3MBTL1KMT2ANPY1R | |
| SCHEMBL7714189 | 0.85 | KMT2A (0.46) | L3MBTL1KMT2ANPY1R | |
| SCHEMBL7936884 | 0.79 | KMT2A (0.56) | L3MBTL1KMT2ASCN9ANPY1R | |
| SCHEMBL7927436 | 0.79 | KMT2A (0.56) | L3MBTL1KMT2ASCN9ANPY1R | |
| SCHEMBL6818563 | 0.79 | KMT2A (0.56) | L3MBTL1KMT2ASCN9ANPY1R | |
| SCHEMBL7718985 | 0.74 | NPY1R (0.45) | L3MBTL1KMT2ASCN9ANPY1R | |
| SCHEMBL7718989 | 0.74 | NPY1R (0.45) | L3MBTL1KMT2ASCN9ANPY1R | |
| SCHEMBL7714012 | 0.74 | SLC6A5 (0.41) | XIAPL3MBTL1KMT2AS1PR1S1PR5 | |
| SCHEMBL7714015 | 0.74 | SLC6A5 (0.41) | XIAPL3MBTL1KMT2AS1PR1S1PR5 | |
| SCHEMBL7214087 | 0.73 | ACACB (0.42) | L3MBTL1KMT2ASCN9ANPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |