Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718985 | 1.00 | NPY1R (0.45) | NPY1RKMT2AL3MBTL1F10HDAC1 | |
| SCHEMBL7927436 | 0.88 | KMT2A (0.56) | NPY1RKMT2AL3MBTL1HDAC1HDAC8 | |
| SCHEMBL6818563 | 0.88 | KMT2A (0.56) | NPY1RKMT2AL3MBTL1HDAC1HDAC8 | |
| SCHEMBL7936884 | 0.88 | KMT2A (0.56) | NPY1RKMT2AL3MBTL1HDAC1HDAC8 | |
| SCHEMBL1065805 | 0.87 | SCN9A (0.50) | NPY1RKMT2ASIGMAR1SCN9A | |
| SCHEMBL1065804 | 0.87 | SCN9A (0.50) | NPY1RKMT2ASIGMAR1SCN9A | |
| SCHEMBL7714192 | 0.86 | KMT2A (0.46) | NPY1RKMT2AL3MBTL1F10 | |
| SCHEMBL7714189 | 0.86 | KMT2A (0.46) | NPY1RKMT2AL3MBTL1F10 | |
| SCHEMBL2332156 | 0.86 | FNTA (0.46) | NPY1RKMT2AL3MBTL1BRD4 | |
| SCHEMBL22911243 | 0.83 | ALDH1A1 (0.51) | NPY1RKMT2AL3MBTL1F10SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |