Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714195 | 1.00 | ITGB1 (0.46) | ITGB1ITGA4PTGS2ELANEMAPT | |
| SCHEMBL7264054 | 0.92 | ITGB1 (0.55) | ITGB1ITGA4PPARG | |
| SCHEMBL7264060 | 0.92 | ITGB1 (0.55) | ITGB1ITGA4PPARG | |
| SCHEMBL7714162 | 0.88 | ELANE (0.37) | ITGB1ITGA4PTGS2ELANEPARP1 | |
| SCHEMBL7714158 | 0.88 | ELANE (0.37) | ITGB1ITGA4PTGS2ELANEPARP1 | |
| SCHEMBL7718457 | 0.84 | ITGA4 (0.56) | ITGB1ITGA4PPARG | |
| SCHEMBL7718460 | 0.84 | ITGA4 (0.56) | ITGB1ITGA4PPARG | |
| SCHEMBL7716190 | 0.83 | ITGB1 (0.54) | ITGB1ITGA4ELANEMAPTPARP1 | |
| SCHEMBL7710671 | 0.83 | ELANE (0.40) | ITGB1ITGA4ELANEMAPTPARP1 | |
| SCHEMBL7710675 | 0.83 | ELANE (0.40) | ITGB1ITGA4ELANEMAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |