Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837340 | 0.83 | KDM4E (1.00) | KDM4EHPGDNPC1RAB9AHSD17B2 | |
| SCHEMBL13269741 | 0.82 | MEN1 (0.55) | KDM4EHPGDNPC1RAB9AHSD17B2 | |
| SCHEMBL18773991 | 0.73 | TP53 (0.62) | HPGDNPC1RAB9AHSD17B2HSD17B1 | |
| SCHEMBL446872 | 0.73 | KCNK3 (0.62) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL29425504 | 0.73 | KCNK3 (0.62) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6796131 | 0.73 | HSD17B2 (0.91) | KDM4EHPGDHSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL14158330 | 0.73 | ACHE (0.53) | KDM4EHPGDNPC1RAB9AHSD17B2 | |
| SCHEMBL10836221 | 0.72 | MEN1 (0.53) | KDM4EHPGDNPC1RAB9AHSD17B2 | |
| SCHEMBL12857682 | 0.72 | KCNK3 (0.61) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2113138 | 0.72 | HSD17B2 (0.66) | KDM4EHPGDNPC1RAB9AHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344359-B1 | COMPLEXING 5,7-DIHALO-8-HYDROXYQUINOLINE IN SOLVENT THAT MINIMIZES VANADYL OXIDATION; COLORIMETRIC ANALYSIS | KINETEK PHARMACEUTICALS, INC. (CA) | 2002-02-05 | — | — | US | disclosed |
| WO-2000008461-A1 | SPECTROPHOTOMETRIC ASSAY FOR THE DETERMINATION OF TOTAL VANADIUM AND THE +IV AND +V OXIDATION STATES OF VANADIUM | KINETEK PHARMACEUTICALS, INC. (CA) | 2000-02-17 | — | — | WO | disclosed |