SCHEMBL446872

SCHEMBL446872

COc1ccc(C(=O)c2cccc(C)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.62
GAA P10253 3/20 0.60
STS P08842 2/20 0.60
ALDH1A1 P00352 1/20 0.60
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 2/20 0.59
NPC1 O15118 1/20 0.59
NFKB1 P19838 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
HPGD P15428 1/20 0.56
TUBB4A P04350 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425504 1.00 KCNK3 (0.62) KCNK3GAASTSALDH1A1RAB9A
SCHEMBL12857682 0.98 KCNK3 (0.61) KCNK3GAASTSALDH1A1RAB9A
SCHEMBL12276577 0.90 STS (0.60) GAASTSALDH1A1RAB9ASMN1; SMN2
SCHEMBL10969744 0.89 ALDH1A1 (0.68) GAASTSALDH1A1RAB9ANPC1
SCHEMBL8808079 0.88 KCNK3 (0.66) KCNK3STSRAB9ASMN1; SMN2TP53
SCHEMBL822041 0.87 PARP1 (0.63) KCNK3ALDH1A1SMN1; SMN2MEN1LMNA
SCHEMBL2303699 0.86 STS (0.72) GAASTSALDH1A1RAB9ASMN1; SMN2
SCHEMBL10014132 0.85 STS (0.56) GAASTSALDH1A1RAB9ANPC1
SCHEMBL16186136 0.85 HSD17B1 (0.58) KCNK3GAASTSALDH1A1RAB9A
SCHEMBL13026416 0.85 STS (0.56) GAASTSALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916283-A Curable conductive composition 贺利氏电子化学材料有限公司 2024-04-19 CN disclosed
US-20240084136-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL MATERIAL CONTAINING SAID CURED PRODUCT MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-14 US disclosed
EP-4282903-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL MATERIAL CONTAINING SAID CURED PRODUCT MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-29 EP disclosed
CN-116829989-A Photocurable composition, cured product thereof, and optical material containing the cured product 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
US-11760898-B2 Hard coating film and window and image display device using same DONGWOO FINE-CHEM CO., LTD. (KR) 2023-09-19 US disclosed
US-11718722-B2 Hard coating film and image display device having the same DONGWOO FINE-CHEM CO., LTD. (KR) 2023-08-08 US disclosed
US-11697749-B2 Multilayer adhesive tape KOZA NOVEL MATERIALS KOREA CO., LTD. 2023-07-11 US disclosed
CN-112592505-B Hard coating film, window comprising same, and image display device 东友精细化工有限公司 2023-06-02 CN disclosed
EP-3656830-B1 ADHESIVE COMPOSITION AND ADHESIVE FILM KOZA NOVEL MAT KOREA CO LTD (KR) 2023-03-29 EP disclosed
US-11613658-B2 Hard coating film and window and image display device using same DONGWOO FINE-CHEM CO., LTD. (KR) 2023-03-28 US disclosed
EP-0860433-B1 QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME KIRIN BREWERY (JP) 2002-07-03 EP disclosed
US-6143764-A ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS KIRIN BEER KABUSHIKI KAISHA (JP) 2000-11-07 US disclosed
EP-0860433-A1 QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME KIRIN BEER KABUSHIKI KAISHA (JP) 1998-08-26 EP disclosed
US-5364944-A Antiinflammatory, antiallergic and cytoprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1994-11-15 US disclosed
US-5218124-A Antiinflammatory agents, antiallergens and cytoprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1993-06-08 US disclosed
US-5071988-A Antiu lcer agents, antiallergens cytoprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1991-12-10 US disclosed
EP-0026609-B1 AROMATIC POLYESTER AND FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP disclosed
EP-0026609-A1 Aromatic polyester and filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-08 EP disclosed
US-4232144-A Polyester which exhibits anisotropy in the melt containing p-oxybenzoyl units and 4-oxy-3'-carbonylbenzophenone units or methyl and chloro derivatives of said units E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-04 US disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed