SCHEMBL837340

SCHEMBL837340

COc1ccc(C(=O)N(O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
HPGD P15428 1/20 1.00
KMT2A Q03164 4/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TSHR P16473 1/20 0.51
OPRM1 P35372 1/20 0.50
OPRL1 P41146 1/20 0.50
ALDH1A1 P00352 4/20 0.49
HTT P42858 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.48
ACHE P22303 1/20 0.48
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873994 0.85 HPGD (0.72) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2111928 0.84 KDM4E (0.73) KDM4EHPGDKMT2ACES2CES1
SCHEMBL7714246 0.83 KDM4E (0.70) KDM4EHPGDKMT2AHSD17B1HSD17B2
SCHEMBL529976 0.83 KDM4E (0.71) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2113520 0.83 KDM4E (0.71) KDM4EHPGDKMT2ACES2CES1
SCHEMBL7865528 0.81 KDM4E (0.69) KDM4EHPGDKMT2ACES2CES1
SCHEMBL133668 0.81 KDM4E (0.67) KDM4EHPGDKMT2ACES2CES1
Hydrochloric Acid SCHEMBL11845983 0.80 KDM4E (0.67) KDM4EHPGDKMT2ACES2CES1
SCHEMBL23511690 0.80 HPGD (0.66) KDM4EHPGDKMT2AHSD17B1HSD17B2
SCHEMBL2112561 0.79 KDM4E (0.66) KDM4EHPGDKMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4727818-B2 2011-07-20 JP claimed
CN-1206921-C Antimicrobial composition comprising an oxidoreductase and an enhancing agent of the N-hydroxy anilide-type NOVO JYMEZ AS (DK) 2005-06-22 CN claimed
US-6592867-B2 Capable of killing or inhibiting microbial cells or micro-organisms in laundry, on hard surfaces, in water systems, on skin, on teeth or on mucous membranes NOVOZYMES A/S (DK) 2003-07-15 US claimed
EP-1128730-B1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES AS (DK) 2003-05-02 EP claimed
JP-2002529380-A 2002-09-10 JP claimed
US-20020094331-A1 ANTIMICROBIAL COMPOSITION CONTAINING AN OXIDOREDUCTASE AND AN ENHANCER OF THER N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2002-07-18 US claimed
CN-1325270-A Antimicrobial composition comprising an oxidoreductase and an enhancing agent of the N-hydroxy anilide-type NOVO JYMEZ AS (DK) 2001-12-05 CN claimed
EP-1128730-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE Novozymes A/S (DK) 2001-09-05 EP claimed
WO-2000027204-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2000-05-18 WO claimed
WO-2025242789-A1 METHOD FOR PRODUCING REINFORCED TEXTILE FIBER COMPOSITIONS LIGAMORE APS (DK) 2025-11-27 WO disclosed
EP-3444337-B1 METHOD OF CLEANING PROCTER & GAMBLE (US) 2024-12-18 EP disclosed
EP-3444336-B1 CLEANING AGENT PROCTER & GAMBLE (US) 2024-05-08 EP disclosed
US-20210147765-A9 CLEANING KIT THE PROCTER AND GAMBLE COMPANY 2021-05-20 US disclosed
US-20210071117-A9 CLEANING AGENT THE PROCTER AND GAMBLE COMPANY 2021-03-11 US disclosed
EP-1128730-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE Novozymes A/S (DK) 2001-09-05 EP disclosed
WO-2001048304-A1 PROCESS FOR REMOVAL OF EXCESS DISPERSE DYE FROM PRINTED OR DYED TEXTILE MATERIAL NOVOZYMES A/S (DK) 2001-07-05 WO disclosed
WO-2001023513-A1 PARTICLES FOR LIQUID COMPOSITIONS NOVOZYMES A/S (DK) 2001-04-05 WO disclosed
WO-2001010195-A1 REDUCTION OF MALODOUR IN SOILED ANIMAL LITTER NOVOZYMES A/S (DK) 2001-02-15 WO disclosed
WO-2000068324-A2 ENZYMATIC PRESERVATION OF WATER BASED PAINTS NOVOZYMES A/S (DK) 2000-11-16 WO disclosed
WO-2000027204-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094331-A1 ANTIMICROBIAL COMPOSITION CONTAINING AN OXIDOREDUCTASE AND AN ENHANCER OF THER N-HYDROXYANILIDE-TYPE LPO, MPO, LCT KDM4E 2516/4885HPGD 45/4885KMT2A 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.