Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947365 | 0.92 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL29683518 | 0.92 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL2166539 | 0.85 | NPC1 (0.44) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL31460799 | 0.83 | MAPT (0.70) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL490810 | 0.83 | MAPT (0.70) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL2115724 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL4875547 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1MAPTKDM4EHSD17B10MAPK1 | |
| SCHEMBL467497 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL31650126 | 0.78 | ACHE (0.51) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL1160244 | 0.78 | ACHE (0.51) | ALDH1A1MAPTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0123750-B1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE INC (US) | 1995-04-26 | — | — | EP | disclosed |
| US-4625026-A | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections | BIOMEASURE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0123750-A1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE, INC. (US) | 1984-11-07 | — | — | EP | disclosed |