Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100555 | 1.00 | ADRB2 (0.31) | ADRB2ADRB1ADRB3PRKG1 | |
| SCHEMBL7714678 | 0.91 | NR1H2 (0.34) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7714681 | 0.91 | NR1H2 (0.34) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7714510 | 0.88 | SSTR4 (0.30) | — | |
| SCHEMBL7714509 | 0.88 | SSTR4 (0.30) | — | |
| SCHEMBL7716950 | 0.86 | ADRB2 (0.32) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8901284 | 0.83 | ADRB3 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7716904 | 0.82 | AOC3 (0.36) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6432465 | 0.81 | ADRB3 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6432460 | 0.81 | ADRB3 (0.52) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865421-B1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LTD (GB) | 2002-03-27 | — | — | EP | disclosed |
| US-6048872-A | DIETETICS; ANTIDIABETIC AGENTS; CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO WELLCOME INC. (US) | 2000-04-11 | — | — | US | disclosed |