Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716942 | 0.91 | AOC3 (0.38) | AOC3S1PR3CASRADRB3BACE1 | |
| SCHEMBL7716940 | 0.91 | AOC3 (0.38) | AOC3S1PR3CASRADRB3BACE1 | |
| SCHEMBL5950226 | 0.86 | AOC3 (0.35) | AOC3S1PR3ADRB3BACE1CPB2 | |
| SCHEMBL5949849 | 0.84 | AOC3 (0.36) | AOC3S1PR3BACE1CPB2 | |
| SCHEMBL5949847 | 0.84 | AOC3 (0.36) | AOC3S1PR3BACE1CPB2 | |
| SCHEMBL6437304 | 0.84 | AOC3 (0.36) | AOC3S1PR3BACE1CPB2 | |
| SCHEMBL4474573 | 0.83 | ADRB3 (0.39) | AOC3MEN1KMT2AADRB3BACE1 | |
| SCHEMBL4474577 | 0.83 | ADRB3 (0.39) | AOC3MEN1KMT2AADRB3BACE1 | |
| SCHEMBL7714567 | 0.82 | ADRB2 (0.31) | ADRB3ADRB2ADRB1 | |
| SCHEMBL8100555 | 0.82 | ADRB2 (0.31) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865421-B1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LTD (GB) | 2002-03-27 | — | — | EP | disclosed |