Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714567 | 0.83 | ADRB2 (0.31) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8100555 | 0.83 | ADRB2 (0.31) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6432465 | 0.82 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6432460 | 0.82 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714681 | 0.82 | NR1H2 (0.34) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714678 | 0.82 | NR1H2 (0.34) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7716904 | 0.82 | AOC3 (0.36) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL6436830 | 0.81 | ADRB1 (0.42) | ADRB3ADRB1ADRB2BACE1 | |
| SCHEMBL6436884 | 0.80 | MCHR1 (0.40) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6436877 | 0.80 | MCHR1 (0.40) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021666-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1997-06-19 | — | — | WO | disclosed |