Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 11/20 | 0.48 |
| ▸ | DAO | P14920 | 4/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712467 | 0.91 | PLA2G7 (0.50) | PLA2G7DAO | |
| SCHEMBL4245709 | 0.81 | AOC3 (0.54) | PLA2G7DAONPC1HTTRAB9A | |
| SCHEMBL10655643 | 0.80 | LMNA (0.60) | PLA2G7 | |
| SCHEMBL226272 | 0.78 | HRH1 (0.55) | DAOCAPN1 | |
| SCHEMBL25101188 | 0.73 | LMNA (0.68) | HTTSMN1; SMN2 | |
| SCHEMBL7708037 | 0.72 | AOC3 (0.51) | PLA2G7DAO | |
| Trifluoroacetic Acid SCHEMBL4245210 | 0.72 | AOC3 (0.44) | DAO | |
| SCHEMBL10733027 | 0.72 | LMNA (0.58) | PLA2G7 | |
| SCHEMBL2626827 | 0.70 | AOC3 (0.62) | DAOCAPN1 | |
| Hydrochloric Acid SCHEMBL25237890 | 0.70 | EGLN1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-6440965-B1 | Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system | KRENITSKY PHARMACEUTICALS, INC. | 2002-08-27 | — | — | US | disclosed |