Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17590311 | 0.81 | TSHR (0.50) | FFAR1TDP1L3MBTL1DPP4ALDH1A1 | |
| SCHEMBL25181550 | 0.81 | TSHR (0.50) | FFAR1TDP1L3MBTL1DPP4ALDH1A1 | |
| SCHEMBL16315019 | 0.80 | CYP1A2 (0.45) | FFAR1TDP1L3MBTL1DPP4PLAAT3 | |
| SCHEMBL12400797 | 0.79 | FFAR1 (0.47) | FFAR1TDP1L3MBTL1DPP4ALDH1A1 | |
| SCHEMBL11825954 | 0.78 | S1PR2 (0.47) | FFAR1TDP1L3MBTL1DPP4ALDH1A1 | |
| SCHEMBL17726118 | 0.77 | NPC1 (0.44) | FFAR1TDP1L3MBTL1DPP4ALDH1A1 | |
| SCHEMBL16148061 | 0.76 | KIF11 (0.54) | FFAR1TDP1L3MBTL1DPP4CYP1A2 | |
| SCHEMBL28741540 | 0.76 | KIF11 (0.54) | FFAR1TDP1L3MBTL1DPP4CYP1A2 | |
| SCHEMBL16148063 | 0.76 | KIF11 (0.54) | FFAR1TDP1L3MBTL1DPP4CYP1A2 | |
| SCHEMBL11827938 | 0.76 | FFAR1 (0.45) | FFAR1TDP1L3MBTL1DPP4PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |